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This compound increases ROS content through autoxidation of neurons, induces oxidative stress, and neurotoxicity (cell death) (39)

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12) was quantified using the BacTiter-Glo Microbial Cell Viability Assay (product G8230, Promega, Madison, WI), according to the manufacturers instructions

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Frequently, brain tumor and its therapy are endocrinologically devastating for children, and the most common residua are growth failure or short stature, which may be caused by the high rate of GHD in children after cranial radiation and radiation effects on skeletal growth after spinal or whole-body radiation treatment (Schriock et al., 1991)

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