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In animal models, BPC-157 improved functional, structural, and biomechanical outcomes in muscle, tendon, ligament, and bony injuries.5 The peptide appears to exert effects through upregulation of VEGF (angiogenesis), activation of FAK/paxillin pathways (cell adhesion and proliferation), stimulation of nitric oxide synthesis (cytoprotection), and increased growth hormone receptor gene expression

Minotti, G

As a result, the autophagy process could be hindered

Then, SUMO attachments are removed by SUMO-specific isopeptidases just like UCHs and UBPs remove ubiquitin from substrate proteins

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