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The Mtb ANA node consists of the enzymes pyruvate carboxylase (PCA), phosphoenolpyruvate (PEP) carboxykinase (PCK), malic enzyme (MEZ) and Rv1127c that is annotated as pyruvate phosphate dikinase (PPDK)

The brain is particularly vulnerable to oxidative damage due to its high oxygen consumption, abundant lipid content, and relatively low antioxidant capacity [151]

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