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Although 80% of HB patients respond to standard neoadjuvant preoperative chemotherapy based on doxorubicin and cisplatin, approximately 20% of the cases have very poor response and prognosis
This is accompanied by a concurrent increase in hydrogen-producing Prevotella and methanogenic archaea that utilize nitrogen (149, 150)
functionally, it restores electrophysiological integrity, reflected in enhanced amplitudes across all major ERG waveforms (a-wave, b-wave, and oscillatory potentials), suggesting preserved functionality of photoreceptors, bipolar cells, and retinal ganglion cells
The incidence of peripheral edema for saxagliptin 2.5 mg was 3.1%
By interacting with the enzymes responsible for creating pigment, glutathione can shift the balance toward a lighter appearance
It is not clear how the relatively minor abnormalities in fibril structure, often affecting less than 5% of fibrils, lead to rather profound alterations of connective tissue function
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