Pennsylvania's Medicaid coverage of the drugs is expected to cost $1.3 billion in 2025 up from a fraction of that several years ago and is contributing to projections of a multibillion-dollar budget deficit

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Historically, sublingual and buccal delivery faced challenges due to low permeability for large molecules, enzymatic degradation, and limited residence time on the mucosa
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This hormone has several roles: Since metabolism, insulin levels, and hormones are so closely linked, these effects have the potential to impact the reproductive system, too