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For example, it can be used to track the unfolding of globular proteins by observing changes in their retention time, which corresponds to changes in their Stokes radius (Corbett and Roche, 1983

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After reviewing the evidence, the European Medicines Agency recommended updating the product information for semaglutide medicines Ozempic, Rybelsus and Wegovy to list NAION as a side effect classified as very rare , and the World Health Organization issued a safety alert in June 2025

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