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Tirzepatide is a new molecule capable of controlling blood glucose levels by combining the dual agonism of glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptors 87 and it was approved by FDA in May 2022

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In support of the latter, chemogenetic activation of the NTS suppressed consumption of a HFD but did not alter intake of normal chow in drug-nave mice 28

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