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Fresolimumab, a neutralizing monoclonal antibody for all TGF- isoforms, exhibited good tolerance and anti-tumour activity in a phase I trial [326]

Taper only when stability is sustained If symptoms remain controlled and the prescribing clinician agrees that medication need has diminished, taper slowly and monitor sleep, mood, anxiety, impulsivity, psychosis, suicidality and functional stability

PMID: 27708183

10.1155/2019/4128152 91 SchieberM.ChandelN

1 There are two different forms of glutathione: reduced glutathione (GSH, or L-glutathione), which is the active form, and oxidized glutathione (GSSG), the inactive state

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