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"These Phase 2 data suggest eloralintide could offer a promising tolerability profile without compromising on efficacy, underscoring the potential of amylin receptor agonists to expand our therapeutic strategies and better serve individuals living with obesity." In the trial, all doses of eloralintide delivered clinically meaningful improvements compared to placebo for the secondary endpoints of reductions in body weight and body mass index

Conflicts of Interest The other authors declare no conflicts of interest

Fatigue was corroborated using independent scales

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It is primarily caused by autoimmune destruction of the gastric parietal cells, leading to a deficiency in Intrinsic Factor and, consequently, a failure to absorb vitamin B12