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(2010) 105:S161

Tukiainen, T

doi: 10.4088/PCC.20m02889 46

The presence of parakeratosis, spongiosis, extravasated red blood cells, dyskeratotic keratinocytes, and the melanin pigment above the suprabasal layer is a hint that a lesion has been traumatized

The peptide also modulates the activity of both metalloproteinases (which break down damaged proteins) and their inhibitors (TIMPs), suggesting a sophisticated regulatory role that balances tissue synthesis with appropriate remodeling