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In contrast, a group of mice that received a control instead of the drug had significant tumor growth over the three-week treatment course

doi:10.1002/mc.20741, PMID: 21319226 Yue P, Zhou Z, Khuri FR, Sun SY (2006) Depletion of intracellular glutathione contributes to JNK-mediated death receptor 5 upregulation and apoptosis induction by the novel synthetic triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate (CDDO-Me)