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It also increases subjective perception of discomfort

[9] Concomitant administration of large calcium supplements, thiazide diuretics, or aluminium-containing phosphate binders can potentiate vitamin D-mediated increases in serum calcium or phosphate, demanding periodic laboratory monitoring and dosage adjustments to avert nephrolithiasis or ectopic calcification

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Never reuse needles or syringes, and store ampoules according to manufacturer instructions typically protected from light, stored below the specified temperature, and not frozen

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