They work by: Slowing gastric emptying , which prolongs feelings of fullness Reducing appetite through effects on brain centres that regulate hunger Improving insulin secretion and glucose metabolism Potentially reducing food intake and affecting eating behaviours These injections are administered subcutaneously, typically once weekly (semaglutide) or once daily (liraglutide), and have been approved by the MHRA for weight management in adults with a BMI 30 kg/m, or 27 kg/m with weight-related comorbidities, as an adjunct to reduced-calorie diet and increased physical activity
Asthma exacerbation counts were lower in those patients who started GLP-1 RAs (reference) compared with SGLT-2 inhibitors [incidence rate ratio (IRR), 2.98
Most patients notice reduced appetite within the first one to two weeks as the medication reaches therapeutic levels
These changes often include: More visible cellulite Looser or deflated appearance of the thighs Reduced volume in the legs Skin that appears uneven or creased Areas where fat loss unmasks existing skin quality issues These changes are common and rooted in predictable physiology, not a sign of something wrong. Understanding why they happen can help you make informed, empowered decisions about your body and your options
The treatment itself is relatively painless, you will be in the salon for around 30 minutes depending on the area being treated
The exposure to excessive stress can cause damage of the cellular membrane or myelin sheath, resulting in axons dysfunctions that can be the origin of neurological diseases 2,3,4
