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Ahlenius H, Kokaia Z

These antibodies are used to treat a variety of solid and blood tumors and include anti-CTLA-4 antibodies (ipilimumab), anti-PD-1 antibodies (nivolumab, pembrolizumab), and anti-PD-L1 antibodies (atezolizumab, durvalumab, avelumab)

Tests in bacteria, cells, and mice all came back negative, suggesting the compound does not pose carcinogenic risk through DNA damage mechanisms

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