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Digestive symptoms such as persistent diarrhea, abdominal pain, rectal bleeding, unexplained weight loss, fever, severe bloating, food intolerance patterns, or nighttime bowel movements deserve medical attention

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Within body tissues, the specific B12 binding proteins transcobalamin I and II facilitate the absorption of cyanocobalamin into the cells.1017 Cyanocobalamin is a cofactor for the synthesis of two major enzymes in the body namely methionine synthase and L-methymalonyl-CoA mutase

Patients with B-12 deficiency along with a history of excessive alcohol intake and poor dietary intake may have underlying malabsorption conditions