Compounded formulations typically have shorter stability windows than brand-name products
It improves insulin sensitivity, has a modest effect on appetite, and has decades of safety data behind it
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While compounded drugs are not FDA-approved, certain compounding may be permitted under sections 503A and 503B of the Federal Food, Drug, and Cosmetic Act in limited circumstances (such as drug shortages)
182 Furthermore, the guidelines do not differentiate recommendations based on the indication for GLP-1RAs use (eg, diabetes versus obesity) or the specific surgical procedure
