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Ethics statement Ethical approval was not required for the studies on humans in accordance with the local legislation and institutional requirements because only commercially available established cell lines were used

Am J Physiol 1992

High-quality randomized trials focused specifically on weight outcomes in non-deficient populations would clarify these uncertainties

The enzyme CHAC1 (CHAC1/BOTCH for blocking NOTCH) is a key regulator of this process (Figure 6)

It can also increase the levels of anti-inflammatory cytokines, such as IL-10 and IL-4

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