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Patient selection for the 10mg dose should encompass glycemic status and prior response to 5mg, weight loss targets, renal function, cardiovascular risk profile, retinopathy status, history of pancreatitis or gallbladder disease, and the patients experience of gastrointestinal adverse reactions during prior escalation steps

J Neuroinflammation 16(1):217 Jiang L, Zhang Y, Jing F, Long T, Qin G, Zhang D, Chen L, Zhou J (2021) P2 7R-mediated autophagic impairment contributes to central sensitization in a chronic migraine model with recurrent nitroglycerin stimulation in mice

Neurological Pathophysiology: Covers diseases such as Alzheimer's, Parkinsons, multiple sclerosis, epilepsy, etc

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Animal tests have also shown that ferroptosis can occur in the uterus of pregnant women with PCOS, making the endometrium less receptive