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For example, a recent ICER review concluded that a new gene therapy for a rare blood disorder would provide good value, even at a one-time cost for a single patient exceeding $2 million (presumably to be covered by insurance)

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Optimal grids for AMYR:Cagri complexes and CTR: Cagri ( N = 1) were imaged by conventional cryo-TEM on a Thermo Fisher Scientific Titan Krios microscope operated at an accelerating voltage of 300 kV with a 50 m C2 aperture and a 100 m objective aperture at an indicated magnification of 105kx in nanoprobe EFTEM mode, yielding a calibrated pixel sampling of 0.85 .pix -1