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This is also supported by Migliorini et al

Biomaterials Research

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Hypoxia also has a role in promoting the expression of prooxidant enzymes such as myeloperoxidase (MPO) and inducible nitric oxide synthase (iNOS) in human uterine fibroid cells, leading to decreased apoptosis [7,34]

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Meta-analysis of efficacy and safety of new oral anticoagulants (dabigatran, rivaroxaban, apixaban) versus warfarin in patients with atrial fibrillation