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doi: 10.1016/j.jhep.2018.05.036, 14

[22] This modern biochemical research resulted in the identification of glutathione S -transferases in 1961, [23] followed by the discovery of cytochrome P450s in 1962, [24] and the realization of their central role in xenobiotic metabolism in 1963

Interleukin-22: a likely target for treatment of autoimmune diseases

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Additionally, the procedure can be painful, deterring many from choosing this method