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[1] The data is clear that these medications do a lot of good

Blood Concentration Achieved A 1000mg IV push puts 1000mg in your bloodstream within minutes

Published mouse-to-human dose conversion factors typically apply factors of 12-15x reduction per kg

Arbabi L, Li Q, Henry BA, Clarke IJ (2021) Glucagon-like peptide-1 control of GnRH secretion in female sheep

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25 mg daily for the oral pill to achieve comparable blood levels