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Semaglutide is the active ingredient in Wegovy

a more gradual reduction (0.51 kg per week) may be better tolerated hormonally than rapid loss

Immune checkpoint inhibitor combination therapies very frequently induce secondary adrenal insufficiency

34,35 Subsequently, GLP-1 undergoes enzymatic degradation facilitated by dipeptidyl peptidase IV (DPP-4), leading to the loss of its biological efficacy

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