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1D), the mRNA and protein expression levels of GLP-1R were significantly increased in ASM cells transfected with pcDNA3.1-Glp-1R for 72 h, and significantly decreased in those transfected with GLP-1R siRNA for 48 h

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AschnerPKipnesMSLuncefordJKSanchezMMickelCWilliams-HermanDEet al

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For current market leaders, sustained dominance will hinge on an ability to navigate an increasingly uncertain regulatory and pricing environment and manage quality and safety concerns amid heightened scrutiny of GLP-1 drugs long-term effects and off-label use