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Most users notice some effect within the first week, but the full appetite-suppressing benefit develops over several weeks as the body adjusts to the compound

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This creates enormous variation in the market

If response is inadequate after the FDA-recommended evaluation period at therapeutic doses, consider switching to an alternative agent or referring for surgical revision evaluation in appropriate candidates

We can either ignore that reality or engage it with honesty, boundaries, and harm reduction, while pushing hard for the kind of research that should have existed before this became mainstream

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