(In full transparency, her team disclosed that Williamss husband, Alexis Ohanian, is a Ro investor and on the board.) Below, Williams talks to ELLE about why she decided to start using a GLP-1 and the diet-culture myths she hopes the drug will help dismantle
[16] [17] Healthcare professionals should provide clear written and verbal instructions on site rotation during treatment initiation and reinforce these principles at follow-up appointments
Increased fat accumulation around the pubic area can partially obscure visible penile length
Many researchers who think they need split dosing actually need better titration
Tirzepatide SURMOUNT-1 (2022) and SURPASS-2 (2021) SURMOUNT-1 (Jastreboff et al., NEJM 2022): 2,539 non-diabetic adults with BMI 30, 72 weeks of tirzepatide 15 mg/week: Weight loss: 20.9% (vs 3.1% placebo) 91% of participants 5% loss, 56.7% 20% SURPASS-2 (Fras et al., NEJM 2021): 1,879 T2D patients head-to-head vs semaglutide 1 mg: HbA1c: 2.30% (tirzepatide 15 mg) vs 1.86% (semaglutide) Weight loss: 11.2 kg vs 5.7 kg Tirzepatide statistically outperforms semaglutide on both HbA1c and weight in a head-to-head trial a rare outcome in incretin pharmacology
doi: 10.1124/pr.117.014803
