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Maintain or enhance muscle definition lost during weight loss

While nausea can occur with setmelanotide, it has a different side effect profile than GLP-1 medications

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Weight change 2 years after termination of the intensive lifestyle intervention in the look AHEAD study

These mechanistic findings provide a biological foundation for the CV benefits observed in clinical trials and support further exploration of novel incretinbased therapies across cardiometabolic disorders

That distinction matters, because most of the content out there is getting this wrong