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Effects of fumarates on circulating and CNS myeloid cells in multiple sclerosis

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In addition, supplementing SAW mice with -HB increased markers of early muscle regeneration and reduced the expression of class IIa histone deacetylases (22), which are known factors that inhibit the regeneration pathway by suppressing myocyte enhancer factor 2 (73)

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Their fibrotic activity was suppressed by treatment with a TGFB signaling inhibitor 24

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