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49 Bulk and single-nucleus RNA-seq analyses of muscle biopsies across the lifespan identified reduced MuSC abundance with age and downregulation of ECM-related genes

Salahuddin A, Ashraf A, Ahmad K, Hou H

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EBioMedicine 28 , 194209 (2018)

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This stress orchestrates a cascade of detrimental events: hepatocellular damage, inflammation, fibrosis, and the activation of hepatic stellate cells, leading to liver fibrosis