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Women with PCOS tend to have increased inflammation and fewer circulating antioxidants, making NAC a helpful supplement

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Metformin-treated MSG-animals responded to ACh better than untreated MSG-rats

This autophagic response reduces cell damage by activating the Keap1/Nrf2 antioxidant pathway, which is associated with Kelch-like ECH protein 1 and nuclear factor erythroid 2-related factor 2, thereby mitigating inflammation, endoplasmic reticulum stress, and apoptosis