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Pathogenesis of Parkinson's disease
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The mutual interactions between the SUMP, emerging sustainable and just mobility practices , and rising discourses on sustainable and just urban mobility is carried out
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It also interfaces with intracellular signaling networks connected to oxidative balance and cellular stress-response mechanisms
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While ROS scavenging is beneficial in chronic diseases like diabetes (Zhang et al., 2020), excessive antioxidant supplementation may disrupt redox homeostasis, as evidenced by increased cancer risk in vitamin E trials ( Antioxidants, which include both enzymatic (e.g., SOD, CAT) and non-enzymatic agents (e.g., ALA, polyphenols), counteract ROS by restoring redox balance and modulating inflammatory and apoptotic pathways
