Moore KJ, Sheedy FJ, Fisher EA
GLP-1 is an incretin hormone: it is released from intestinal L-cells in response to nutrient ingestion and, among other actions, potentiates glucose-dependent insulin secretion, suppresses glucagon, slows gastric emptying, and acts on central circuits to reduce appetite and food intake
The substantial barriers to access to GLP-1s reflect existing inequities and poor alignment of incentives in our healthcare system, says study coauthor Katherine Hempstead, senior policy officer at the Robert Wood Johnson Foundation
Such consequences will ultimately hinder tissue regeneration and repair processes (Sies and Jones, 2020
Macrophages act as master controllers of all tissue healing phases
The TLR3 agonist poly (I:C) prevents DSS-induced colitis (Zhong and Kyriakis, 2004)