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Moore KJ, Sheedy FJ, Fisher EA

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GLP-1 is an incretin hormone: it is released from intestinal L-cells in response to nutrient ingestion and, among other actions, potentiates glucose-dependent insulin secretion, suppresses glucagon, slows gastric emptying, and acts on central circuits to reduce appetite and food intake

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The substantial barriers to access to GLP-1s reflect existing inequities and poor alignment of incentives in our healthcare system, says study coauthor Katherine Hempstead, senior policy officer at the Robert Wood Johnson Foundation

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Such consequences will ultimately hinder tissue regeneration and repair processes (Sies and Jones, 2020

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Macrophages act as master controllers of all tissue healing phases

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The TLR3 agonist poly (I:C) prevents DSS-induced colitis (Zhong and Kyriakis, 2004)

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