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doi: 10.1016/j.neuron.2025.03.032

Torchen LC, Legro RS, Dunaif A

Two first peptides are 36 amino-acid long peptides that act via G-protein receptor subtypes-Y1, Y2, Y3, Y4, Y5 and Y6 mediating the overlapping physiological actions of PP-family peptides

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Cryo-EM maps have been deposited in the Electron Microscopy Data Bank under the following accession codes: for the CagriCTRG s complex, EMD-64557 (raw map), EMD-64558 (receptor-focused refinement map), and EMD-64560 (composite map)

The responses of serum glucose, insulin, C-peptide, and plasma glucagon to 2 mg glimepiride were unaffected by coadministration of ramipril (an ACE inhibitor) 5 mg once daily in normal subjects