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An Orphan Molecule, and the Leap to Injuries Patents last twenty years
To explore gene expression changes, a multivariate reanalysis of the GSE1073233 dataset was performed, revealing major differences between untreated HepG2 and HepG2 ATP7B-KO cells, particularly in autophagy, lipid metabolism, and stress-related pathways
The pellets were resuspended in RIPA buffer and centrifuged at 14,000 g to acquire nuclear extracts
So, while they show promising results so far, whether this effect translates to humans, needs more research to answer
[DOI] [PMC free article] [PubMed] [Google Scholar] 72.Rangwala S., Rashid R.M
Gediya, L.K
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