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Other periodontal pathogens, including Klebsiella , Streptococcus , and Veillonella , can endure harsh acidic environments and migrate to the intestine, particularly in individuals with weakened oralgut chemical barriers (bile and gastric acid), such as infants, people with gastrointestinal disease, individuals using proton-pump inhibitors (PPIs), and elderly people (Azzolino et al., 2025

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* Correspondence: Jinhao Zeng, [email protected]

Intravenous high-dose vitamin C has caused very few side effects in clinical trials

Mechanism The precise mechanisms underlying these adverse psychiatric effects remain unclear

Thats because levels of endogenous GH peak at these times