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These structures are generally formed in the first and second trimesters of fetal development

Overall, DPP4i have a favourable therapeutic profile and are safe and effective in the majority of patients with type 2 diabetes mellitus

The pathogenesis of obesity is multifaceted with environmental, socio-cultural, physiological, medical, behavioral, genetic, and epigenetic factors (2)

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Therapeutic interventions are aimed at either increasing elimination of the parent drug or enhancing cytoprotective pathways to reduce the cytotoxic effects