glutathione synthetase

glutathione synthetase Inborn errors in the metabolism of | Orphanet Journal of Rare Diseases Glutathione Synthase - an overview

Name: glutathione synthetase Inborn errors in the metabolism of | Orphanet Journal of Rare Diseases Glutathione Synthase - an overview
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In vitro experiments have shown that GSH deficiency induced by either the siRNA approach or pharmacological inhibition of the GCL rate-limiting enzyme decreases GSH biosynthesis and escalates oxidative stress in cultured hepatocytes

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The results showed that NAC provided minor improvements in pregnancy and ovulation rates compared to other treatments like metformin when used to treat unexplained infertility