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Additionally, adequate maternal B12 is crucial for both mother and child, supporting maternal health and reducing the risk of neurological and metabolic complications

2 Transforming the immunosuppressive prostate cancer tumor microenvironment: from cold to hot with peptides The TME of PCa is distinguished by T cell exhaustion and immunosuppressive activity of Treg cells, M2 macrophages, and quiescent NK cells (Kang et al., 2022)

Notably, administration of GEP44 resulted in an 80% reduction in food intake and a more profound loss of body weight than what could be achieved in response to treatment with several of the US Food and Drug Administration (FDA)-approved GLP-1RAs, including Ex-4 and liraglutide (LIRA)

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In contrast, ascorbate deficiency enhances susceptibility to the necrotrophic pathogen Alternaria brassicicola , in which defence is mediated by jasmonic acid and ethylene signalling (Botanga et al