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The impaired apolipoprotein B-100 synthesis in NASH patients could be related to the increased cellular FFA level, disturbed redox balance, hyperinsulinemia and decreased expression, all of which were shown to hamper apolipoprotein B-100 synthesis and VLDL assembly, thus resulting in lipid accumulation in the liver [39]

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Neuroprotective effects of peroxisome proliferator-activated receptor alpha and gamma agonists in model of parkinsonism induced by intranigral 1-methyl-4-phenyl-1,2,3,6-tetrahyropyridine

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