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As anticipated, chemical inhibition of SLC7A11 by erastin lowered intracellular GSH and GSH:GSSG (Figure 4A)
It is designed for administration into the nasal cavity, providing targeted local or systemic effects through the nostrils
A pilot clinical trial found that liposomal glutathione raised whole-blood GSH by up to 40% and PBMC glutathione by up to 100% within two weeks at 500-1,000 mg/day
doi: 10.3346/jkms.1998.13.5.513 112 AoyagiKKoufujiKYanoSMurakamiNTerasakiYYamasakiYet al
2009a;484(2):1839
Some individuals may require ongoing maintenance to keep their desired results
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