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These cells secrete various mediators that are directly responsible for the progression of allergy and bronchial obturation in asthma ( de novo synthesized prostaglandin D2 (PGD2), leukotriene C4 (LTC4), adenosine, and ROS are released from mast cell granules ( Figure 1 )

CpG-DNA enhances the tight junction integrity of the bronchial epithelial cell barrier

Statistical analysis All data are represented as mean + standard deviation

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