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This review therefore builds upon a previous review by Gonzalez and Trexler (2020) who recently discussed the efficacy CM ingestion to improve exercise performance within a larger, more general review of NO enhancing supplements, by offering a more in-depth discussion on the potential mechanisms associated with CM supplementation

Considering the retrospective design, certain data points are lacking, as they were originally documented for clinical monitoring purposes rather than for the explicit intent of this study

Phase III Clinical Trials The pivotal Phase III clinical trial program for HSDD in premenopausal women enrolled over 1,200 participants across two identical randomized, double-blind, placebo-controlled trials

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Generally: a BMI of 30+ (obesity) or BMI of 27+ with weight-related conditions like hypertension, type 2 diabetes, or high cholesterol

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