Recently, Nicassio and colleagues suggested an influence of acetyl-l-carnitine on mitochondria homeostasis in the brains of old rats [96]
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(2007, 2010), in vitro mechanistic study (Hauff et al., 2009), and animal model (Han et al., 2007) indicated that higher demand for cholesterol synthesis (e.g., for cell grow or LDL-cholesterol increases) is detrimental to mitochondrial cardiolipin content