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In some embodiments, a formulation described herein, further comprises a gelling agent (e.g., poloxamer 407) and provides release of the therapeutic agent over a period of from about 2 days to about 7 days

ROS activate antioxidant pathways, protecting cancer cells from oxidative damage [74]

doi: 10.3389/fendo.2020.608733 Received 21 September 2020 Accepted 13 November 2020 Published 14 December 2020 Volume 11 - 2020 Edited by Marian Elizabeth Ludgate, Cardiff University, United Kingdom Reviewed by Utta Berchner-Pfannschmidt, Essen University Hospital, Germany

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