The primary treatment for MNTI is surgical resection, although there are examples of MNTI treatment using chemotherapy alone
In the context of male rat spermatogenesis, the extract of ursolic acid was found to impede the physiological maturation of sperm, evident by decreased sperm count and motility, potentially attributed to the depletion of testosterone at the target level (Sun et al., 2020)
And the exciting thing
Recent evidence further demonstrates its capacity to modulate gut microbiota composition, rectifying homocysteine-methionine metabolic imbalance and attenuating cardiovascular risks (Liu et al., 2013
doi: 10.3389/fphar.2025.1438318 Received 31 May 2024 Accepted 11 April 2025 Published 15 May 2025 Volume 16 - 2025 Edited by Bernd Rosenkranz, Fundisa African Academy of Medicines Development, South Africa Reviewed by C
The transcription factors ATF4 and Nrf2 couple ER stress to a general cellular response that increases the production of glutathione by increasing aminoacid metabolism (Cullinan et al , 2003
