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GLP-1 type medications mimic a natural hormone called GLP-1 (glucagon-like peptide-1) which regulates appetite and food intake

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Genetic Factors in Peptide Signaling: Emerging Personalization Tools Recent research has identified genetic variants in GLP-1 receptor, GIPR (glucose-dependent insulinotropic polypeptide receptor), and energy-regulation pathways (FTO, MC4R) that may influence how individuals respond to GLP-1 therapy

Exercise and physical activity in mental disorders: clinical and experimental evidence

The post uses this to argue that satiety and metabolic improvement are two outputs of the same mechanism