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Patients with pre-existing cardiovascular conditions, uncontrolled hypertension, or structural cardiac abnormalities require particularly cautious evaluation, and stimulants may be contraindicated in certain high-risk individuals

Statistical analyses were performed using GraphPad Prism 9.5 (GraphPad Software, San Diego, CA, USA)

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Pal HC, Pearlman RL, Afaq F

British journal of cancer 128(1):130-136, 2023

While GLP- 1 RAs were initially exploited for their effects on insulin sensitivity and glucagon secretion, the Nutrient Stimulated Hormones being targeted have effects on muscle protein synthesis and even energy expensiture [42,43,44]