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Efficacy FDA approval was supported by the Phase III OASIS-4 study, in which patients taking oral Wegovy achieved an average weight loss of 16.6%, compared with 2.7% in the placebo group

10.1016/s0140-6736(17)30058-2 180 Su WoongJ.JaeYoungM

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Conversely, rodent-specific tumor findings prompted regulatory warnings that continue to influence labeling despite uncertain relevance to humans