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Fernandes-Santos, C

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The onset of clinical benefit in this secondary analysis therefore precedes substantial weight loss and predates the achievement of target maintenance dosing, although the time-to-benefit estimates carry wider confidence intervals than the primary endpoint

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Conclusions This body of work demonstrates the development and validation of assays using a tissue chip platform for high-content drug screening and the successful discovery and in vivo validation of candidate radioprotective drugs with non-antioxidant primary modes of action