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Catalase and Cardiovascular Diseases Cardiovascular disease encompasses a broad range of conditions affecting the heart and blood vessels, with coronary heart disease, exemplified by the accumulation of plaque leading to atherosclerosis, commonly equated with heart disease. Plaque buildup, comprising calcium, fat, cholesterol, and other blood components, narrows arteries, impedes oxygen-rich blood flow, and may cause angina or precipitate blood clots, leading to heart attacks

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11 , e1004210 (2015)